An image of exosome sacs with showing their growth factor molecules

What Are Exosomes?

Exosomes reduce inflammation, speed healing, optimize skin rejuvenation and hair restoration treatments, and help skin function better at a cellular level.

Exosomes are know for dramatic improvement in fine lines, wrinkles, scars, enlarged pores, loose skin, rough skin, hyperpigmentation, and hair restoration.

Rejuvience Med Spa employs a variety of medical grade exosome products to help prepare skin for rejuvenation treatment, speed treatment healing, and optimize skin rejuvenation treatment results. So what are exosomes?

Exosomes are tiny sacs called vesicles that are made in our bodies by stem cells. The tiny sacs contain growth factors, peptides, and other vital biosignaling molecules. The tiny sacs travel across cell membranes to deliver their healing and regenerative cargo directly into the cell.

What Types of Exosomes Are There?

Exosomes can be natural or engineered, and they have human or plant origins. 

Natural Exosomes

Natural exosomes in regenerative aesthetics products have human origins. They are produced by mesenchymal stem cells, a type of stem cell found in different types of tissue. Mesenchymal (meh-suhng-kai-muhl) stem cells are ideal source for producing exosomes that signal the body to regenerate tissue. 

In your body these cells naturally produce the growth factors, peptides, and other molecules that accelerate and amplify wound healing resulting in rejuvenated skin that functions better at a cellular level. The most commonf sources of mesenchymal stem cells are bone marrow (AnteAGE products), adipose (fat) tissue (BENEV products), and umbilical cord tissue (AnteAGE products).

Engineered Biosomes

The new AntiAGE Biosome products are synthetic human exosomes. The healing molecules in biosomes are bioidentical to those in natural human exosomes. There is no need for human cells or conditioned media in the manufacturing process.

Plant Exosomes

Plant exosomes contain bioactive molecules derived from plant cells. Also called plant-derived exosome-like nanoparticles (PDENs), plant exosomes contain bioactive biomolecules and have the potential to deliver nano-bioactive compounds.

Human vs Plant Exosomes - What's Different?

Plant exosomes are key to intercellular communication and molecular transport in plants. Human exosomes are key to intercellular communication and molecular transport in humans. The healing molecules in plant exosomes for plants can alleviate inflammation in human tissue, however they can’t signal human tissue regeneration. Human cells do not have receptors for the plant healing molecules. 

Which Exosome Products Do You Carry?

We carry a variety of medical grade natural and engineered exosomes products. Some are dispensed in-clinic as part of a skin rejuvenation procedure. Others are available for home care.

Our exosome product selection is based on routine evaluations of all exosome products in all available medical grade product lines. Our selection criteria includes registered USA manufacturing, product ingredient formulation, and demonstrated clinical efficacy. 

Which Treatments Include In-Clinic Exosomes?

Exosomes to augment skin rejuvenation treatments are especially recommended for addressing visible signs of aging skin, hyperpigmentation, and distressed skin conditions such as rosacea.    

Medical grade exosomes applied in-clinic are available to augment Tixel Skin Resurfacing, Procell MicroChanneling, Exceed Medical Microneedling treatments. Exosomes are the foundation of our Age Repair Trifecta.  

Some Exosome FAQs

Do Exosomes Really Work?

Yes, exosomes really do work. 

Augmenting today’s advanced skin rejuvenation treatments with exosomes dramatically improves intercellular communication and tissue regeneration. They are clinically proven to shrink skin rejuvenation treatment healing windows, deliver optimal results, and improve skin health by helping skin function better at a cellular level.

 

Do Exosomes Tighten Skin?

Yes, exosomes tighten skin. 

They act as messengers that stimulate collagen and elastin production. These proteins give skin it firmness (elastin) and plumpness (collagen). More collagen and more elastin plumps and firms skin, which in turn given skin a tighter, smoother surface.  

 

Do Exosomes Work for Hair Loss?

Exosomes can work for hair loss, however results may be temporary. 

From a research perspective, there are some studies that show a statistically significant increase in hair density after exosome therapy for hair loss. Those who respond typically see results in 10 to 12 weeks, however hair may fall out again after the series treatments ends. 

This is because hair loss can be caused by lots of different things. Micronutrient deficiency, protein deficiency, autoimmune disease, thyroid disorders, sex hormone imbalances, diabetes, COVID infection, genetics, aging, and stress are well documented factors. Treatment expectations are better met when nutritional deficiencies, hormone issues, blood sugar issues, and stress have been ruled out.     

 

Recent Exosome Science

Harsha Sreeraj, R. AnuKiruthika, K.S. Tamilselvi, D. Subha. (2024, December). Exosomes for skin treatment: Therapeutic and cosmetic applications, Nano TransMed, Volume 3. https://doi.org/10.1016/j.ntm.2024.100048 

Abstract: The therapeutic potential of exosomes, which are nano-sized extracellular vesicles derived from various cell types, have drawn substantial interest in the field of dermatology. Exosomes have distinctive capabilities, including facilitating intercellular communication, delivering bioactive molecules, and modulating immune responses, which make them promising candidates for skin regeneration, wound healing, and treating dermatological disorders. Specifically, exosomes derived from the stem cells of mesenchymal and adipose cells, have numerous applications in skin repair and regeneration. Exosomes also find expanded applications in treatments and therapies related to hair. Exosomes emit signals and growth factors that impact the activity of nearby epithelial cells, encouraging their growth, specialization, and the development of hair formations. This review explores the efficacy of topical and transdermal applications of exosomes in skin and hair and highlight the transformative potential of exosome-based therapies in dermatology and pave the way for future research and clinical applications.

Complimentary Skincare at Consultation Rejuvience Med Spa Scottsdale

Not sure which mix of treatments and/or products is best for your concerns? Book a complimentary consultation.

There’s no cost, and there’s no obligation. During your appointment we’ll discuss your concerns and treatment options. 

We understand we are not the right fit for everyone, and we do refer out when we think a different specialist will be of more help.